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Saizen HGH is a prescription drug for children whose growth has slowed or stopped because their bodies do not produce or release enough growth hormone. Saizen® is most commonly called HGH or Somatropin. It is manufactured to meet FDA standards for quality and purity for Serono labs which manufactures Saizen.

How does Saizen HGH work?

Saizen stimulates growth of bones, cells, and organs. Clinical studies have shown that it causes a decrease in body fat and an increase in bone growth and muscle mass.

Who should not take Saizen HGH?

Patients who should not take Saizen hgh if they have recently been hospitalized with a serious trauma or critical condition or require a respirator to breathe. Patients having open heart surgery or major surgery on the stomach, intestine or bowel should not take Saizen.

The bacteriostatic water that comes with Saizen HGH contains the preservative benzyl alcohol, which should not be used in newborns or patients with a known sensitivity to benzyl alcohol. For these patients, Saizen may be reconstituted with Sterile Water for Injection, USP. When it is reconstituted in this manner, it must be used immediately and any unused portion must be discarded.

Saizen HGH may trigger insulin resistance and should be used with caution in patients who have diabetes mellitus or a family history of diabetes mellitus. Inform your doctor of any diabetes in the patient's family.

Saizen should not be used in patients who have active cancerous or benign tumors. Patients with a history of cancer should be monitored closely.

How should Saizen hgh be taken?

Saizen can be taken with the cool.click™ needle-free delivery device or with a needle and syringe. The basic steps for preparing and using Saizen are outlined here. Your doctor, nurse, or other healthcare provider will help you learn to perform these steps. Follow their instructions carefully.

• Wash your hands before you begin.
  
  
• Mix (reconstitute) one vial of Saizen with the amount of sterile diluent your doctor has prescribed. Your doctor, nurse, or other healthcare provider will explain the mixing process in detail.
  
  
• After mixing, gently swirl the mixture in the vial until the powder is dissolved. Do not shake. The liquid should be clear. If it is cloudy, prepare another vial.
  
  
• Withdraw the prescribed amount of Saizen using the cool.click™ needle-free delivery device or a needle and syringe.
  
  
• Choose a delivery site and clean it with an alcohol wipe. The best sites are those with a layer of fat between the skin and muscle, like the thigh, the back of the upper arm, the abdomen and the rear end. Use a different site every time, and do not deliver Saizen® to an area of the body where the skin is irritated, reddened, or bruised.
  
  
• Deliver Saizen HGH as directed.
  
  
• Apply pressure to the site using a gauze pad or cotton ball.
  
  
• If you use needles, dispose of them properly in a biohazardous waste container. Do not reuse needles or syringes.

Talk to your doctor if you have any concerns about treatment or notice any changes in the patient's health, including the following:

• Difficulty breathing or the appearance of a skin rash or hives. Call your doctor right away because this could be an allergic reaction, which is a potentially serious medical condition.
• Diagnosis of any form of cancer.
• Excessive thirst, increased urination, or dizziness. These could be symptoms of overdose or glucose intolerance.
• Unusual headaches, problems with eyesight, nausea, or vomiting. These have been observed in a small number of patients and usually occurred within the first eight weeks of therapy.

What are the possible side effects of taking Saizen HGH?

As with any medicine, report any and all side effects, symptoms, or physical changes to your doctor.

In clinical studies in which Saizen was given to children with growth hormone deficiency, the following reactions were infrequently seen: pain, numbness, redness, or swelling at the delivery site, hypothyroidism (low thyroid hormone), hypoglycemia (low blood sugar), seizures or convulsions, water retention, and worsening of psoriasis symptoms that existed before therapy began.

Any patient who has a growth hormone deficiency and does not respond to therapy should be tested for thyroid problems or antibodies to human growth hormone. Either of these conditions can reduce the effectiveness of the drug.

Leukemia has been reported in a small number of patients. It is not clear whether this is the result of the growth hormone deficiency itself, growth hormone therapy, or other associated treatments such as radiation therapy for brain tumors. So far, data has failed to confirm a relationship between growth hormone therapy and leukemia.

When growth hormone is given at the same site over a long period of time, the tissue can become damaged. This problem can be avoided by switching among several different sites (such as the thighs, rear end, abdomen, and backs of the arms).

How do I store Saizen HGH?

Before you mix them, vials of Saizen powder should be stored at room temperature between 59° and 86° F (15°-30° C).

Saizen that has been mixed with the sterile diluent (Bacteriostatic Water for Injection, USP) must be refrigerated (36°-46° F/2°-8° C) and can be used for 28 days. Avoid freezing. Do not use Saizen after the expiration date.

What happens if I miss a dose of Saizen HGH?

Call your doctor or nurse immediately to report any missed doses.

Where can I get more information about Saizen HGH?

This page is a summary of important patient information about Saizen. If you have any questions or problems, talk to your doctor or healthcare provider.. Saizen is manufactured and distributed by Serono, Inc. You can call Serono's patient information program, Connections for Growth, at 800-582-7989. Important: Please do not use this phone number for reporting Adverse Events. Instead, call the Product Information and Surveillance Group at 888-ASK-SERO (888-275-7376). For a medical emergency, call your local doctor or 911.